Jacoby Brissett Shines But Cardinals Lose Heartbreaker to Colts - NFL Game Recap (2025)

Despite Jacoby Brissett's Stellar Performance, Cardinals Fall Short Against Colts

INDIANAPOLIS – Jacoby Brissett, returning to the team he once started 30 games for, showcased his prowess in a thrilling match against the Cardinals. Despite his outstanding performance, the Cardinals couldn't secure a win, falling short in a heart-wrenching manner.

Brissett, stepping in for the injured Kyler Murray, led the Cardinals to a season-high 400 yards of offense, even after losing wide receiver Marvin Harrison Jr. to a concussion in the first half. He completed 27 out of 44 passes for 320 yards, two touchdowns, and one interception, just six yards shy of his career best. The Cardinals' offensive prowess was on full display, but it wasn't enough to secure the victory.

Coach Jonathan Gannon emphasized that Murray remains the starting quarterback when he returns, but the timeline for his return remains uncertain. The Cardinals have a crucial home game against the Packers before their bye week, adding to the anticipation and pressure.

Brissett's performance was met with praise from Gannon, who highlighted his poise and command in the pocket. Despite his impressive display, the Cardinals' fate was sealed in the final moments, leaving them with a bitter taste of defeat.

The turning point came when the Colts scored the go-ahead touchdown with 4:32 left on a Jonathan Taylor run, as the Cardinals' defense struggled to contain the Indianapolis offense. The Colts dominated each possession in the second half, except for the final run-out-the-clock situation.

Key players stood out, including Brissett, who led the offense with precision. Tight end Trey McBride and wide receiver Zay Jones also made significant contributions, with McBride catching eight passes for 72 yards and a touchdown, and Jones amassing five catches for 79 yards. However, the Cardinals' inability to convert in the final moments left them frustrated.

Injury updates were also a concern, with tight end Travis Vokolek sustaining a neck/concussion injury and being carted off the field after a collision during a first-quarter kickoff. The team has already lost tight end Tip Reiman for the season. Additionally, wide receiver Marvin Harrison Jr. suffered a concussion in the second quarter, and running back Emari Demercado exited the game with an ankle injury in the first quarter.

The Cardinals' recent string of close losses has been disheartening, with all six games decided in the final 60 seconds. The team's resilience and determination were on full display, but the bitter taste of defeat lingered, leaving them searching for a breakthrough.

Jacoby Brissett Shines But Cardinals Lose Heartbreaker to Colts - NFL Game Recap (2025)
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